Choline

Choline

Choline is technically a “vitamin-like factor,” although it sometimes is referred to as a B vitamin. The body can produce a small amount of choline, but we also must get some either from our diet or a supplement. Choline is an essential part of all body tissues.

Some of the best sources of choline are:

  • Eggs
  • Beef liver
  • Chicken liver
  • Soybeans
  • Beef
  • Pork
  • Mutton
  • Veal
  • Fish
  • Shrimp
  • Milk
  • Peanuts
  • Peanut butter
  • Nuts, particularly:
    • Cashews
    • Macadamia nuts
    • Pine nuts
    • Pecans
    • Walnuts
    • Pistachios
  • Green leafy vegetables
  • Iceberg lettuce
  • Cauliflower
  • Kale
  • Brussels sprouts
  • Cabbage
  • Grape juice
  • Oranges
  • Whole milk
  • Tomatoes
  • Whole-wheat bread
  • Wheat germ
  • Oat bran
  • Milk chocolate
  • Decaffeinated instant coffee powder

You need choline because it:

  • Is a part of an important neurotransmitter that is necessary for:
    • Sleep
    • Muscle movement
    • Regulation of  pain
    • Learning
    • Memory
  • Helps to maintain the structure of cellular membranes
  • Aids in the transmission of nerve impulses
  • Assists in the absorption of fat
  • Is necessary for the removal of fat and cholesterol from the body
  • Reduces chronic inflammation
  • Is a part of lung surfactant
  • Is necessary for the kidney’s control of water balance within the body

Choline also may help:

  • Keep short-term memory loss from occurring in people with Alzheimer’s disease
  • Prevent cardiovascular disease
  • Relieve symptoms of Huntington’s disease in high doses
  • Decrease total cholesterol, while favorably increasing high-density lipoprotein (HDL) levels
  • Prevent gallstones
  • Improve liver function
  • Decrease the risk of developing liver cancer
  • Decrease sensitivity to carcinogenic chemicals
  • Reduce the risk of neural tube defects

Signs and symptoms of choline deficiency
The following are the signs and symptoms of choline deficiency:

  • Fatty liver and liver damage
  • Muscle weakness
  • Tingling in the fingers and toes
  • Fatigue
  • Weakness

The following individuals are at risk for choline deficiency:

  • Strict vegetarians
  • Endurance athletes
  • People who drink alcohol
  • Men and postmenopausal women (choline deficiency more likely than in premenopausal women)

Choline toxicity
The upper limit of toleration for choline is 3.5 grams (g). Symptoms of choline toxicity include:

  • Fishy body odor
  • Diarrhea
  • Vomiting
  • Excessive salivation
  • Excessive sweating
  • Low blood pressure

Daily intake
The US Institute of Medicine recommends an adequate daily intake of 550 milligrams (mg)/day for men and 425 mg/day for women.

References and recommended readings

Egg Nutrition Center. Eggs are an excellent source of choline. Available at: http://www.enc-online.org/factsheet/Choline.pdf. Accessed October 27, 2008.

George Mateljan Foundation. Choline. Available at: http://www.whfoods.com/genpage.php?tname=nutrient&dbid=50. Accessed October 27, 2008.

Howe JC, William JR, Holden JM. USDA database for the choline content of common foods. Available at: http://www.nal.usda.gov/fnic/foodcomp/Data/Choline/Choline.pdf. Accessed October 27, 2008.

Oregon State University, Linus Pauling Institute. Choline. Available at: http://lpi.oregonstate.edu/infocenter/othernuts/choline/index.html#function. Accessed October 27, 2008. 

University of Pittsburgh Medical Center. Choline. Available at: http://nutritionservices.upmc.com/NutritionArticles/Vitamins/Choline.htm. Accessed October 27, 2008.

Wood M. B vitamins choline and folate scrutinized. Available at: http://www.ars.usda.gov/is/pr/2001/010330.htm. Accessed October 27, 2008. 

 

Review Date 12/08
G-0891

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